https://centre.santafe.edu/complextime/w/index.php?title=Aging_in_Single-celled_Organisms:_from_Bacteria_to_the_Whole_Tree_of_Life/LinChao&feed=atom&action=historyAging in Single-celled Organisms: from Bacteria to the Whole Tree of Life/LinChao - Revision history2024-03-28T10:30:48ZRevision history for this page on the wikiMediaWiki 1.35.6https://centre.santafe.edu/complextime/w/index.php?title=Aging_in_Single-celled_Organisms:_from_Bacteria_to_the_Whole_Tree_of_Life/LinChao&diff=5494&oldid=prevLinChao at 19:29, February 12, 20202020-02-12T19:29:56Z<p></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:29, February 12, 2020</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A. What is aging? Classical definition from Medawar aging is passage of time and aging is the deterioration of function with time. Aging and senescence is nowadays used to mean equivalently the deterioration with time. We will used aging and senescence in this more contemporary context, and refer to the passage of time specifically as chronological aging. However, because in some organisms the deterioration can be reversed, we will describe those instances as reversed or positive senescence or aging (discuss?).</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A. What is aging? Classical definition from Medawar aging is passage of time and aging is the deterioration of function with time. Aging and senescence is nowadays used to mean equivalently the deterioration with time. We will used aging and senescence in this more contemporary context, and refer to the passage of time specifically as chronological aging. However, because in some organisms the deterioration can be reversed, we will describe those instances as reversed or positive senescence or aging (discuss?).</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>B. Following Medawar, we also can distinguish aging that results from wear and tear from interactions with the environment much as a automobile parked by the ocean will rust and fragment. However, because the hallmark that distinguishes physical objects such as a car and a biological organism is the latter's ability to change through evolution by natural selection, aging can be accelerate in living systems beyond physical wear and tear. The acceleration results from the production of asymmetrical daughters by dividing mother cells. While the asymmetry can result from a combination of factors, some beneficial and others deleterious, a possible cause may be damaged cellular molecules and organelles. <del class="diffchange diffchange-inline">Because</del></div></td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>B. Following Medawar, we also can distinguish aging that results from wear and tear from interactions with the environment much as a automobile parked by the ocean will rust and fragment. However, because the hallmark that distinguishes physical objects such as a car and a biological organism is the latter's ability to change through evolution by natural selection, aging can be accelerate in living systems beyond physical wear and tear. The acceleration results from the production of asymmetrical daughters by dividing mother cells. While the asymmetry can result from a combination of factors, some beneficial and others deleterious, a possible cause may be damaged cellular molecules and organelles. <ins class="diffchange diffchange-inline">The daughter that receives more damage ages and the other rejuvenates. The aging daughter can be viewed as the continuation of the mother, the daughter receiving less can be regarded as the new juvenile offspring. This concept can be extended to metazoans and the asymmetry</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr>
</table>LinChaohttps://centre.santafe.edu/complextime/w/index.php?title=Aging_in_Single-celled_Organisms:_from_Bacteria_to_the_Whole_Tree_of_Life/LinChao&diff=5485&oldid=prevLinChao at 16:29, February 12, 20202020-02-12T16:29:51Z<p></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 16:29, February 12, 2020</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l4" >Line 4:</td>
<td colspan="2" class="diff-lineno">Line 4:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A. What is aging? Classical definition from Medawar aging is passage of time and aging is the deterioration of function with time. Aging and senescence is nowadays used to mean equivalently the deterioration with time. We will used aging and senescence in this more contemporary context, and refer to the passage of time specifically as chronological aging. However, because in some organisms the deterioration can be reversed, we will describe those instances as reversed or positive senescence or aging (discuss?).</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A. What is aging? Classical definition from Medawar aging is passage of time and aging is the deterioration of function with time. Aging and senescence is nowadays used to mean equivalently the deterioration with time. We will used aging and senescence in this more contemporary context, and refer to the passage of time specifically as chronological aging. However, because in some organisms the deterioration can be reversed, we will describe those instances as reversed or positive senescence or aging (discuss?).</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>B. Following Medawar, we also can distinguish aging that results from wear and tear from interactions with the environment much as a automobile parked by the ocean will rust and fragment. However, because the hallmark that distinguishes physical objects such as a car and a biological organism is the latter's ability to change through evolution by natural selection, aging can be accelerate in living systems beyond physical wear and tear. The acceleration results from the <del class="diffchange diffchange-inline">accumulation</del></div></td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>B. Following Medawar, we also can distinguish aging that results from wear and tear from interactions with the environment much as a automobile parked by the ocean will rust and fragment. However, because the hallmark that distinguishes physical objects such as a car and a biological organism is the latter's ability to change through evolution by natural selection, aging can be accelerate in living systems beyond physical wear and tear. The acceleration results from the <ins class="diffchange diffchange-inline">production of asymmetrical daughters by dividing mother cells. While the asymmetry can result from a combination of factors, some beneficial and others deleterious, a possible cause may be damaged cellular molecules and organelles. Because</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr>
</table>LinChaohttps://centre.santafe.edu/complextime/w/index.php?title=Aging_in_Single-celled_Organisms:_from_Bacteria_to_the_Whole_Tree_of_Life/LinChao&diff=5479&oldid=prevLinChao at 00:08, February 12, 20202020-02-12T00:08:19Z<p></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 00:08, February 12, 2020</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l4" >Line 4:</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A. What is aging? Classical definition from Medawar aging is passage of time and aging is the deterioration of function with time. Aging and senescence is nowadays used to mean equivalently the deterioration with time. We will used aging and senescence in this more contemporary context, and refer to the passage of time specifically as chronological aging. However, because in some organisms the deterioration can be reversed, we will describe those instances as reversed or positive senescence or aging (discuss?).</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A. What is aging? Classical definition from Medawar aging is passage of time and aging is the deterioration of function with time. Aging and senescence is nowadays used to mean equivalently the deterioration with time. We will used aging and senescence in this more contemporary context, and refer to the passage of time specifically as chronological aging. However, because in some organisms the deterioration can be reversed, we will describe those instances as reversed or positive senescence or aging (discuss?).</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>B. Following Medawar, we also can distinguish aging that results from wear and tear from interactions with the environment much as a automobile parked by the ocean will rust and fragment. However, because the hallmark that distinguishes physical objects such as a car and a biological organism is the latter's ability to change through evolution by natural selection, aging can be accelerate in living systems beyond physical wear and tear.</div></td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>B. Following Medawar, we also can distinguish aging that results from wear and tear from interactions with the environment much as a automobile parked by the ocean will rust and fragment. However, because the hallmark that distinguishes physical objects such as a car and a biological organism is the latter's ability to change through evolution by natural selection, aging can be accelerate in living systems beyond physical wear and tear. <ins class="diffchange diffchange-inline"> The acceleration results from the accumulation</ins></div></td></tr>
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</table>LinChaohttps://centre.santafe.edu/complextime/w/index.php?title=Aging_in_Single-celled_Organisms:_from_Bacteria_to_the_Whole_Tree_of_Life/LinChao&diff=5473&oldid=prevLinChao: Created page with "{{Attendee note |Post-meeting summary=Outline A. What is aging? Classical definition from Medawar aging is passage of time and aging is the deterioration of function with..."2020-02-11T23:57:35Z<p>Created page with "{{Attendee note |Post-meeting summary=Outline A. What is aging? Classical definition from Medawar aging is passage of time and aging is the deterioration of function with..."</p>
<p><b>New page</b></p><div>{{Attendee note<br />
|Post-meeting summary=Outline<br />
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A. What is aging? Classical definition from Medawar aging is passage of time and aging is the deterioration of function with time. Aging and senescence is nowadays used to mean equivalently the deterioration with time. We will used aging and senescence in this more contemporary context, and refer to the passage of time specifically as chronological aging. However, because in some organisms the deterioration can be reversed, we will describe those instances as reversed or positive senescence or aging (discuss?).<br />
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B. Following Medawar, we also can distinguish aging that results from wear and tear from interactions with the environment much as a automobile parked by the ocean will rust and fragment. However, because the hallmark that distinguishes physical objects such as a car and a biological organism is the latter's ability to change through evolution by natural selection, aging can be accelerate in living systems beyond physical wear and tear.<br />
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