Cognitive Regime Shift II - When/why/how the Brain Breaks/GaganWig

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Notes by user Gagan Wig (UT Dallas) for Cognitive Regime Shift II - When/why/how the Brain Breaks

Post-meeting Reflection

1+ paragraphs on any combination of the following:

• Presentation highlights
• Open questions that came up
• How your perspective changed
• Impact on your own work
• e.g. the discussion on [A] that we are having reminds me of [B] conference/[C] initiative/[D] funding call-for-proposal/[E] research group

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Reference material notes

Some examples:

• Here is [A] database on [B] that I pull data from to do [C] analysis that might be of interest to this group (insert link).
• Here is a free tool for calculating [ABC] (insert link)
• This painting/sculpture/forms of artwork is emblematic to our discussion on [X]!
• Schwartz et al. 2017 offers a review on [ABC] migration as relate to climatic factors (add the reference as well).

In addition to bridging genetic and cellular to the cognitive and behavioral levels, an examination and integration of broader levels of complexity can further our understanding of when/why/how the brain breaks. I propose that this can be achieved by understanding how an individual’s lifestyle and environment relate to their resilience and vulnerability to brain decline.

I’m sharing a story (D. Buettner, NY Times, 2012) that begins to describe how multiple complex systems (including social, cultural, physiological, technological) may be important to consider for thinking about the health and robustness of an individual. I’m also sharing an article (Chan et al., PNAS, 2018) that summarizes my lab’s first attempt at integrating methods that examine an individual’s psycho-social environment with measures of their brain network organization to begin to understand the types of features that may lead to variability in brain network aging.

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Reference Materials

Title	Author name	Source name	Year	Citation count From Scopus. Refreshed every 5 days.	Page views	Related file
The Island Where People Forget to Die - The New York Times		New York Times Magazine	2012	0	6	Download
Socioeconomic status moderates age-related differences in the brain’s functional network organization and anatomy across the adult lifespan2		Proceedings of the National Academy of Sciences	2018	0	4	Download Download

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