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1+ paragraphs on any combination of the following:
Noteworthy concepts and questions:
#Ravi: "Gerontropy". In additional to directional changes in health indicators do we get an increase in variance?
#Alfons: Multiscale approaches. Do multiple length and time scales really matter when they are separated? Can interdependence network approach be improved to take into account hierarchical structures of organs/tissues/cells/molecules?
#Ravi, Chhanda: How can theorists make themselves useful for NIH? How to communicate "theoretically driven" projects to NIH?
#Chhanda: Resilience builds up over time. Effect of early life history on aging. Comparative biology approaches e.g. naked mole rat
#Ravi, Chhanda: Very interesting plasticity effect: Physiological state does not come back exactly to the same point after perturbation. A theoretical description of physiological elasticity vs. plasticity
#Ingrid: Idea on multiple tipping points that are coupled. I recommend checking out Kramer's escape problem. Chhanda excellent question: Are young ecosystems more resilient, just like young people. Alfons had an excellent question: what can you say about the dynamics by knowing only qualitative causal relationships. An idea: if there are multiple models describing the same subsystems and their interactions, can these be combined/reconciled to get a result more accurate than all models individually?
#Peter: Potentially useful model but one should be careful about drawing conclusions from single runs. e.g. Flipping coins would also yield similar ups and downs if one looked at individual runs. It would be good to check if the model gives Gompertz (exponential) mortality curves or Weibull. I would also have critical questions about sensitivity to parameters and system size, i.e. if the damage rate was close to repair rate I suspect that the system would never collapse (given large system size).
#Heather. Very interesting conceptual graph derived from a real patient where multiple systems failing at different times at different rates. This resonates with Chhanda's observation that resilience is not one thing, but a multi-dimensional vector.