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Dynamic Multi-System Resilience in Human Aging/Welcome & introduction around the Room - Revision history
2024-03-28T22:36:23Z
Revision history for this page on the wiki
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Wikiworks at 19:32, June 25, 2019
2019-06-25T19:32:00Z
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Wikiworks
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Wikiworks at 21:02, January 20, 2019
2019-01-20T21:02:47Z
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Wikiworks
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Wikiworks at 20:57, January 20, 2019
2019-01-20T20:57:47Z
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|Is presentation=Yes</ins></div></td></tr>
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Wikiworks
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Wikiworks: Replaced content with "{{Agenda item |Start time=November 12, 2018 09:30:00 AM |End time=November 12, 2018 09:45:00 AM |Presenter=MarcelGMOldeRikkert;TimBuchman }}"
2019-01-20T18:05:12Z
<p>Replaced content with "{{Agenda item |Start time=November 12, 2018 09:30:00 AM |End time=November 12, 2018 09:45:00 AM |Presenter=MarcelGMOldeRikkert;TimBuchman }}"</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 18:05, January 20, 2019</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Presenter=MarcelGMOldeRikkert;TimBuchman</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Presenter=MarcelGMOldeRikkert;TimBuchman</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">|Post-meeting notes=I was amazed by the alternative vision of Dervis Can Vural about damage accumulation and aging in random network perspective. Among others it again helped me realize that downstream targeted therapies in chronic age related diseases (which mostly are directed by mechanisms of aging) probably are not to be of great help. The connections of nodes higher upstream, still being damaged or producing damage will still end up in causing the disease related decline.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">The presentation of Peter Hofmman showed an elegant 'simple model' of stochastic damage accumulation and repair. It opened the perspective of ramdoness in resilience mechanisms, when the redundancy of reserve function has depleted. The three trajectories of damage and death occurence are very interesting, and I look very much forward to the statistical analyses of these data, after repeated runs of these models.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">The talk of Alfons Hoekstra, showed that the multiscale modeling is fit for supporting resilience research and so is fit for being part of the workshop (though he humbly stated that multiscale modeling might not be mature enough for this challenge). The examples Alfons showed in the time -space scaling diagrammes and the connecting interactions do inspire to connect and likewise model subsystems depending on one another and creating a meaningful representation of challenges for aging persons.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Ravi Varadhan and Chhandi Dutta gave an excellent overview of the research grants given in the field by the NIA, and the models already published, respectively. These are excellent sources of comparison for further work.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Second day, we had a very inspiring lecture of Ingrid vd Leemput. The theoretical and empirical reasoning and analyses of ecosystems can be of great help in studying resilience systems in aging man.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Heather Whitson followed up with a nice clinical example. But not only the patient but also the family and physicians make up a complex adaptive system. She also paved the way to stress tests of different kinds, which was completed later on nicely by Warren Ladiges on animal models. This connection added new insights and clearly showed that beside computational models, the animal models are very valuable.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Last but not least Porter Swetsell gave eye openers on population resilience based on his scholarly and personal experiences with pueblo population resilience over time. These all got intertwined in the group discussion, which also opened up new opportunities for collaboration.</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">The meeting so far showed emergence of many new options, and warrants, inspires aand invites for further interaction and collaboration.</del></div></td><td colspan="2"> </td></tr>
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Wikiworks
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Wikiworks at 03:01, November 22, 2018
2018-11-22T03:01:57Z
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|End time=November 12, 2018 09:45:00 AM</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|End time=November 12, 2018 09:45:00 AM</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Presenter=MarcelGMOldeRikkert;TimBuchman</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Presenter=MarcelGMOldeRikkert;TimBuchman</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|Post-meeting notes=I was amazed by the alternative vision of Dervis Can Vural about damage accumulation and aging in random network perspective. Among others it again helped me realize that downstream targeted therapies in chronic age related diseases (which mostly are directed by mechanisms of aging) probably are not to be of great help. The connections of nodes higher upstream, still being damaged or producing damage will still end up in causing the disease related decline.</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">The presentation of Peter Hofmman showed an elegant 'simple model' of stochastic damage accumulation and repair. It opened the perspective of ramdoness in resilience mechanisms, when the redundancy of reserve function has depleted. The three trajectories of damage and death occurence are very interesting, and I look very much forward to the statistical analyses of these data, after repeated runs of these models.</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">The talk of Alfons Hoekstra, showed that the multiscale modeling is fit for supporting resilience research and so is fit for being part of the workshop (though he humbly stated that multiscale modeling might not be mature enough for this challenge). The examples Alfons showed in the time -space scaling diagrammes and the connecting interactions do inspire to connect and likewise model subsystems depending on one another and creating a meaningful representation of challenges for aging persons.</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Ravi Varadhan and Chhandi Dutta gave an excellent overview of the research grants given in the field by the NIA, and the models already published, respectively. These are excellent sources of comparison for further work.</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Second day, we had a very inspiring lecture of Ingrid vd Leemput. The theoretical and empirical reasoning and analyses of ecosystems can be of great help in studying resilience systems in aging man.</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Heather Whitson followed up with a nice clinical example. But not only the patient but also the family and physicians make up a complex adaptive system. She also paved the way to stress tests of different kinds, which was completed later on nicely by Warren Ladiges on animal models. This connection added new insights and clearly showed that beside computational models, the animal models are very valuable.</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Last but not least Porter Swetsell gave eye openers on population resilience based on his scholarly and personal experiences with pueblo population resilience over time. These all got intertwined in the group discussion, which also opened up new opportunities for collaboration.</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">The meeting so far showed emergence of many new options, and warrants, inspires aand invites for further interaction and collaboration.</ins></div></td></tr>
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Wikiworks
https://centre.santafe.edu/complextime/w/index.php?title=Dynamic_Multi-System_Resilience_in_Human_Aging/Welcome_%26_introduction_around_the_Room&diff=2176&oldid=prev
AmyPChen at 17:24, September 7, 2018
2018-09-07T17:24:14Z
<p></p>
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|End time=November 12, 2018 09:45:00 AM</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Presenter=MarcelGMOldeRikkert;TimBuchman</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|Presenter=MarcelGMOldeRikkert;TimBuchman</div></td></tr>
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AmyPChen
https://centre.santafe.edu/complextime/w/index.php?title=Dynamic_Multi-System_Resilience_in_Human_Aging/Welcome_%26_introduction_around_the_Room&diff=2174&oldid=prev
AmyPChen at 17:23, September 7, 2018
2018-09-07T17:23:11Z
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AmyPChen
https://centre.santafe.edu/complextime/w/index.php?title=Dynamic_Multi-System_Resilience_in_Human_Aging/Welcome_%26_introduction_around_the_Room&diff=2173&oldid=prev
AmyPChen: Created page with "{{Agenda item |Start time=November 12, 2018 12:00:00 AM |Presenter=MarcelGMOldeRikkert;TimBuchman }}"
2018-09-07T17:13:17Z
<p>Created page with "{{Agenda item |Start time=November 12, 2018 12:00:00 AM |Presenter=MarcelGMOldeRikkert;TimBuchman }}"</p>
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AmyPChen