Effects of host heterogeneity on pathogen diversity and evolution
- Category
- General Reference
- author-supplied keywords
- Coexistence
- Competition
- Evolutionary ecology
- Host heterogeneity
- Host-pathogen interactions
- Tradeoffs
- keywords
- authors
- Arietta E. Fleming-Davies
- Vanja Dukic
- Viggo Andreasen
- Greg Dwyer
- title
- Effects of host heterogeneity on pathogen diversity and evolution
- type
- journal
- year
- 2015
- source
- Ecology Letters
- pages
- 1252-1261
- volume
- 18
- issue
- 11
- publisher
- Blackwell Publishing Ltd
- link
- https://www.mendeley.com/catalogue/dc4588eb-2192-3cde-812e-1b5bc5721144/(0)
Abstract
Phenotypic variation is common in most pathogens, yet the mechanisms that maintain this diver- sity are still poorly understood. We asked whether continuous host variation in susceptibility helps maintain phenotypic variation, using experiments conducted with a baculovirus that infects gypsy moth (Lymantria dispar) larvae. We found that an empirically observed tradeoff between mean transmission rate and variation in transmission, which results from host heterogeneity, promotes long-term coexistence of two pathogen types in simulations of a population model. This tradeoff introduces an alternative strategy for the pathogen: a low-transmission, low-variability type can coexist with the high-transmission type favoured by classical non-heterogeneity models. In addi- tion, this tradeoff can help explain the extensive phenotypic variation we observed in field-col- lected pathogen isolates, in traits affecting virus fitness including transmission and environmental persistence. Similar heterogeneity tradeoffs might be a general mechanism promoting phenotypic variation in any pathogen for which hosts vary continuously in susceptibility.
Counts
- Citation count From Scopus. Refreshed every 5 days.
- 33
- Page views
- 2
Identifiers
- doi: 10.1111/ele.12506 (Google search)
- issn: 14610248
- sgr: 84943662364
- isbn: 1461-0248
- pmid: 26365355
- scopus: 2-s2.0-84943662364
- pui: 606016975
