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- Aging and Adaptation in Infectious Diseases II/Session V: Aging and the Arrow of Time –Breakout Group Updates and Broader Themes of the SFI/JSMF Initiative + (Discussion leaders selected from each brea … Discussion leaders selected from each breakout group</br></br>Working group topics may include: </br></br>1. Interaction of the adaptive and innate immune system in the dynamics of infection </br></br>2. the role of early-childhood exposure (‘imprinting’) in later immune protection and in defining the temporal changes of the antigenic map</br></br>3. the allometric scaling of the immune system dynamics with organism size. </br></br>Broader topics may include: </br></br>1. Complex Networks: Architecture, Robustness, and Fragility, </br></br>2. Memory, Dynamics, and Timing, </br></br>3. Scaling and Complex Time. Timing, 3. Scaling and Complex Time.)