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- User:NilesLehman + (I am interested in molecular evolution and … I am interested in molecular evolution and the biochemistry of catalytic RNAs (ribozymes). Research in my lab utilizes powerful in vitro evolution techniques to discover RNA sequences with new or improved functions, for example, in regard to RNA-metal ion interactions. We are particularly keen to use these techniques to test fundamental evolutionary hypotheses, such as the antiquity of recombination.s, such as the antiquity of recombination.)