Santa Fe Institute Collaboration Platform

COMPLEX TIME: Adaptation, Aging, & Arrow of Time

Get Involved!
Contact: Amy P. Chen, Program Manager, amypchen@santafe.edu

Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock

From Complex Time
Category
General Reference
author-supplied keywords
keywords
authors
title
Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock
type
journal
year
2012
source
Cell
pages
46-57
volume
148
issue
1-2
publisher
Elsevier Inc.

Abstract

The underlying cause of aging remains one of the central mysteries of biology. Recent studies in several different systems suggest that not only may the rate of aging be modified by environmental and genetic factors, but also that the aging clock can be reversed, restoring characteristics of youthfulness to aged cells and tissues. This Review focuses on the emerging biology of rejuvenation through the lens of epigenetic reprogramming. By defining youthfulness and senescence as epigenetic states, a framework for asking new questions about the aging process emerges.

Counts

Citation count From Scopus. Refreshed every 5 days.
Page views
4

Identifiers

Add a file