Santa Fe Institute Collaboration Platform

COMPLEX TIME: Adaptation, Aging, & Arrow of Time

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Aging in Single-celled Organisms: from Bacteria to the Whole Tree of Life/SrividyaIyer-Biswas

From Complex Time

Notes by user Srividya Iyer-Biswas (Purdue Univ./SFI) for Aging in Single-celled Organisms: from Bacteria to the Whole Tree of Life

Post-meeting Reflection

1+ paragraphs on any combination of the following:

  • Presentation highlights
  • Open questions that came up
  • How your perspective changed
  • Impact on your own work
  • e.g. the discussion on [A] that we are having reminds me of [B] conference/[C] initiative/[D] funding call-for-proposal/[E] research group

This was an exciting meeting with a lot of animated discussions leading to interesting confluences and diverges of opinions.

Basic questions that came up again and again: What is aging? Given how contextual it is, what is a good operational definition? How to design and refine specific experiments that get to the interplay between asymmetry generation, aging, memory formation, rejuvenation, information processing, statistical learning, energetics, individual specific histories, intrinsic stochasticity in organismal growth, resilience to different perturbations, homeostasis, adaptation, evolvability, plasticity and tradeoffs therein.

I especially enjoyed discussions about new technologies and tools that can be co-opted and added as modules to ongoing experiments to get at some of these exciting questions.

Reference material notes

Some examples:

  • Here is [A] database on [B] that I pull data from to do [C] analysis that might be of interest to this group (insert link).
  • Here is a free tool for calculating [ABC] (insert link)
  • This painting/sculpture/forms of artwork is emblematic to our discussion on [X]!
  • Schwartz et al. 2017 offers a review on [ABC] migration as relate to climatic factors (add the reference as well).

Reference Materials