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- What is Sleep?/Modeling circadian systems: are they the ultimate sleep clock? + (''Elizabeth Klerman – Review of mathematic … ''Elizabeth Klerman – Review of mathematical models of circadian rhythms''</br></br>I will review current mathematical models of circadian rhythms, their inputs, outputs, and structure and then areas in which new work is needed – especially adjustment of models to predict inter-individual differences rather than describe group averages.</br></br>''Cecilia Diniz Behn - Modeling interactions between circadian rhythms and sleep''</br></br>In mathematical models of sleep, representations of circadian rhythmicity determine sleep timing under both entrained and perturbed conditions. I will review the role of circadian rhythms in sleep/wake models and the ways in which the complexity of these representations crucially affects sleep/wake dynamics. crucially affects sleep/wake dynamics. )