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COMPLEX TIME: Adaptation, Aging, & Arrow of Time

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What is Sleep?/Modeling circadian systems: are they the ultimate sleep clock?

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November 18, 2019
11:30 am - 12:30 pm


Elizabeth Klerman (Harvard Medical School)Cecilia Diniz Behn (Colorado School of Mines)


Elizabeth Klerman – Review of mathematical models of circadian rhythms

I will review current mathematical models of circadian rhythms, their inputs, outputs, and structure and then areas in which new work is needed – especially adjustment of models to predict inter-individual differences rather than describe group averages.

Cecilia Diniz Behn - Modeling interactions between circadian rhythms and sleep

In mathematical models of sleep, representations of circadian rhythmicity determine sleep timing under both entrained and perturbed conditions. I will review the role of circadian rhythms in sleep/wake models and the ways in which the complexity of these representations crucially affects sleep/wake dynamics.   

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