# What is Sleep?/Modeling circadian systems: are they the ultimate sleep clock?

**November 18, 2019**

11:30 am - 12:30 pm

- Presenter

**Elizabeth Klerman** (Harvard Medical School), **Cecilia Diniz Behn** (Colorado School of Mines)

- Abstract

*Elizabeth Klerman – Review of mathematical models of circadian rhythms*

I will review current mathematical models of circadian rhythms, their inputs, outputs, and structure and then areas in which new work is needed – especially adjustment of models to predict inter-individual differences rather than describe group averages.

*Cecilia Diniz Behn - Modeling interactions between circadian rhythms and sleep*

In mathematical models of sleep, representations of circadian rhythmicity determine sleep timing under both entrained and perturbed conditions. I will review the role of circadian rhythms in sleep/wake models and the ways in which the complexity of these representations crucially affects sleep/wake dynamics.

- Presentation file(s)

- Related files