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COMPLEX TIME: Adaptation, Aging, & Arrow of Time

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Dynamic Multi-System Resilience in Human Aging/PeterMHoffmann

From Complex Time

Notes by user Peter M. Hoffmann (Wayne State Univ.) for Dynamic Multi-System Resilience in Human Aging

Post-meeting Reflection

1+ paragraphs on any combination of the following:

  • Presentation highlights
  • Open questions that came up
  • How your perspective changed
  • Impact on your own work
  • e.g. the discussion on [A] that we are having reminds me of [B] conference/[C] initiative/[D] funding call-for-proposal/[E] research group

I was concerned that “high-level” models would not be useful in this context, but that turned out not to be the case. It was fascinating to see how actual physiological data can potentially be analyzed and understood in the context of metastable states, complexity, networks, critical states, 1/f noise etc. A full understanding how these things connect and how they relate to real data is still in its infancy, which should make this an exciting area to think about.

The goal will be to "marry" conceptual models and data collected from real systems. How can conceptual models capture stress and perturbation responses, time scales, tipping points & attractors, feedback loops, variability, noise and complexity seen in real systems? Conceptual models should be helpful if we want to learn what measured signals (transient, noise etc.) can tell us about the structure and dynamic state of the underlying system.

Reference material notes

Some examples:

  • Here is [A] database on [B] that I pull data from to do [C] analysis that might be of interest to this group (insert link).
  • Here is a free tool for calculating [ABC] (insert link)
  • This painting/sculpture/forms of artwork is emblematic to our discussion on [X]!
  • Schwartz et al. 2017 offers a review on [ABC] migration as relate to climatic factors (add the reference as well).

Reference Materials

Title Author name Source name Year Citation count From Scopus. Refreshed every 5 days. Page views Related file
Reliability Theory of Aging and Longevity Leonid A. Gavrilov, Natalia S. Gavrilova Handbook of the Biology of Aging 2005 59 0
Reliability Theory of Aging and Longevity4 Leonid A. Gavrilov, Natalia S. Gavrilova J. Theor. Biol. 2001 59 15

Presenter on the following Agenda items

Conceptual models of human aging and resilience

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