Irreversible Processes in Ecological Evolution/JacopoGrilli
Notes by user Jacopo Grilli (ICTP) for Irreversible Processes in Ecological Evolution
1+ paragraphs on any combination of the following:
- Presentation highlights
- Open questions that came up
- How your perspective changed
- Impact on your own work
- e.g. the discussion on [A] that we are having reminds me of [B] conference/[C] initiative/[D] funding call-for-proposal/[E] research group
Connection between population dynamics and strain diversity. What is the response to pathogen intervention? (clear in a Chessonian framework, unclear when there is strong strain diversity). 1) Rotavirus. Robust antigenic diversity. Estimate of the parameters from cases: G-type strong specific immune response, P-type strong general immune response (concern: very few data, enough statistical power). Surprising: no effect of vaccine/intervention. 2) S. pneumonia. Frequency of strains. How does frequency change after intervention? Replicator model, predicted fitness from genes (how? Not clear): can predict frequencies after intervation (which again does not work). Questions: 1) what determines the equilibrium frequencies of genes? Why loci are under negative frequency negative dependent selection?
Reference material notes
- Here is [A] database on [B] that I pull data from to do [C] analysis that might be of interest to this group (insert link).
- Here is a free tool for calculating [ABC] (insert link)
- This painting/sculpture/forms of artwork is emblematic to our discussion on [X]!
- Schwartz et al. 2017 offers a review on [ABC] migration as relate to climatic factors (add the reference as well).
Presenter on the following Agenda items
- Related files