Aging and Adaptation in Infectious Diseases/Session IV: Complex Rhythms, environment, and aging in epidemiology
July 27, 2018
1:00 pm - 3:00 pm
David Schneider (Stanford)
- Presentation file(s)
- Related files
- Jenny Tung (Duke Univ.)
|Citation count From Scopus. Refreshed every 5 days.
|Social status alters immune regulation and response to infection in macaques
|Noah Snyder-Mackler, Joaquín Sanz, Jordan N. Kohn, Jessica F. Brinkworth, Shauna Morrow, Amanda O. Shaver, Jean Christophe Grenier, Roger Pique-Regi, Zachary P. Johnson, Mark E. Wilson, Luis B. Barreiro, Jenny Tung
- Micaela Martinez (Columbia Univ.)
The meeting is composed of expert disease dynamicsmodelers and disease ecologists; thus, my presentation will be focused on chronobiology. Specifically, I will review new data regarding circadian and circannual rhythms in humans and mouse models.
- Andrew P. Dobson (Princeton)
Assemble a talk that describes non-human examples of how host exposure and response to pathogens and disease changes with age.
Describe ways of quantifying age-dependent changes in exposure.
Discuss possible dynamic consequences in variation in duration of incubation and infectivity with age.
Describe models for parasitic nematodes of different sizes living as a community of worms in hosts of different sizes.
Illustrate recent work with Ian Hatton on body size scaling of vital rates from Algae to Elephants - use this to suggest we could use this scaling for models of immune system in mammals (from bats and mice to elephants and whales).
Andrew P. Dobson (Princeton) Link to the source page
Really interesting set of talks that blended into a good set of discussions on projects the group could work on. There will be a big emphasis on human immunity and how it first gains 'experience' and then breaks down with age.
I'm likely to focus my attention on developing body sized scaled models for immune system. These could be both fairly simple models for immunity mainly capturing differences between Type I and Type II immunity, but then expanding this to take Jean Carlson's model for human immunity and rescale elements of this with host body size and BMR.